Health and Equity Disparities Christian Strohm Health and Equity Disparities Christian Strohm

Racism, African American Women, and Their Sexual and Reproductive Health: A Review of Historical and Contemporary Evidence and Implications for Health Equity

Racism in the U.S. is pervasive and is a major contributor to sexual and reproductive health disparities of African American women. The historical narrative about racial inferiority has affected the quality and types of healthcare provided to African American women.

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Health and Equity Disparities Christian Strohm Health and Equity Disparities Christian Strohm

Amplifying Scientific Innovation With Dr. Gary Puckrein, CEO, National Minority Quality Forum (NMQF)

Differences in health status across racial and ethnic groups in the United States have been described for a wide array of diseases, conditions, and outcomes (NCHS, 2000). Despite overall improvements in life expectancy in the past century, African Americans still experience a lower average life expectancy at birth and higher average age-adjusted all-cause death rates than whites.

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Health and Equity Disparities Christian Strohm Health and Equity Disparities Christian Strohm

Increasing Racial and Ethnic Diversity Among Physicians: An Intervention to Address Health Disparities?

Differences in health status across racial and ethnic groups in the United States have been described for a wide array of diseases, conditions, and outcomes (NCHS, 2000). Despite overall improvements in life expectancy in the past century, African Americans still experience a lower average life expectancy at birth and higher average age-adjusted all-cause death rates than whites.

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Kidney Cancer Christian Strohm Kidney Cancer Christian Strohm

Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

  • The molecular profile of RMC distinguishes it from other renal malignancies

  • RMC harbors a high number of focal chromosomal alterations

  • RMC has a distinct immune profile characterized by upregulation of cGAS-STING

  • DNA replication stress is a hallmark of RMC that can be therapeutically targeted

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Sickle Cell Christian Strohm Sickle Cell Christian Strohm

A study of the geographic distribution and associated risk factors of leg ulcers within an international cohort of sickle cell disease patients: the CASiRe group analysis

This cross-sectional cohort sub-study of 659 sickle cell patients aimed to determine the geographic distribution and risk factors associated with leg ulcers. The prevalence of leg ulcers was 10.3% and was associated with older age, SS genotype, male gender, and Ghanaian origin. In fact, the highest prevalence (18.6%) was observed in Ghana.

Albuminuria, proteinuria, increased markers of hemolysis (lower hemoglobin, higher total bilirubin), lower oxygen saturation, and lower body mass index were also associated with leg ulceration.

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Sickle Cell Christian Strohm Sickle Cell Christian Strohm

An Analysis of Racial and Ethnic Backgrounds Within the CASiRe International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research

This is the first report of a comprehensive analysis of ethnicity within an international, transcontinental group of SCD patients. The diverse ethnic backgrounds observed in our cohort raises the possibility that genetic and environmental heterogeneity within each SCD population subgroup can affect the clinical phenotype and research outcomes.

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Breast Cancer Christian Strohm Breast Cancer Christian Strohm

Disparities in Breast Cancer Stage at Diagnosis: Importance of Race, Poverty, and Age

This study investigated the association of race, age, and census tract area poverty level on breast cancer stage at diagnosis. The risk, relative risk, and increased risk of late-stage at diagnosis by race, age, and census tract area poverty level were computed. We found that the odds of late-stage breast cancer among African-American women were higher when compared with their white counterpart (OR 1.433; 95% CI, 1.316, 1.560).

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