Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

Kidney Cancer
Written By Christian Strohm

  • The molecular profile of RMC distinguishes it from other renal malignancies

  • RMC harbors a high number of focal chromosomal alterations

  • RMC has a distinct immune profile characterized by upregulation of cGAS-STING

  • DNA replication stress is a hallmark of RMC that can be therapeutically targeted

Christian Strohm
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